Vistara non-invasive prenatal screening

Vistara identifies risk for conditions that may have otherwise gone undetected until after birth or into childhood.

All conditions are inherited in an autosomal or X-linked dominant fashion, which means that if the mutation is present, the child will be affected by the condition and experience related symptoms.

Vistara facilitates early diagnosis for skeletal, cardiac, and neurological disorders.


Vistara screens cell-free DNA (cfDNA) for serious genetic conditions that affect quality of life and may benefit from medical and/or surgical intervention

Screened conditions include:

  • Noonan syndrome
  • Achondroplasia
  • Osteogenesis imperfecta
  • Rett syndrome
  • And 21 other single-gene disorders across 30 genes


Conditions screened by Vistara have a combined incidence of 1 in 600 – higher than that of Down syndrome.

See all conditions:  Vistara screening at Natera

Vistara identifies risk for single-gene disorders that may have otherwise gone undetected prenatally:

  • Ultrasound findings are not a reliable indicator
  • Conditions are not detected with standard karyotype or microarray analysis
  • Family history is typically not a good indicator of risk (often de novo)
  • Early identification of these conditions is clinically actionable


Consider Vistara for the following indications:

  • advanced paternal age
  • women who want to know “everything” or as an adjunct to CVS and amniocentesis
  • ultrasound anomalies, such as shortened long bones and increased NT

Additional information:

Sample positive report

Tested Conditions List

Vistara Screening brochure