Panorama prenatal test

The Panorama™ prenatal test logo

Introducing the Panorama™ prenatal test, the most accurate and comprehensive non-invasive test that gives you the reassurance you need during your pregnancy.

Natera has a screening non-invasive prenatal test (NIPT) called Panorama that uses a blood sample from mom to find the baby’s DNA and to look for certain chromosome conditions that could affect the baby’s health.

The Panorama test is highly effective in determining if there is only one chromosome where there should be a pair, or if there is an extra chromosome, especially for the chromosomes that are responsible for Down syndrome, Edwards syndrome, Patau syndrome and certain sex chromosome trisomies. Panorama can also identify if there are three sets of each chromosome, which is known as triploidy.

The aim of the Panorama test is to find out if there is any chance of the following disorders:

  1. Trisomy 21 (Down syndrome)
  2. Trisomy 18 (Edwards syndrome)
  3. Trisomy 13 (Patau syndrome)
  4. Triploidy (Triploidy syndrome), which affects 1 out of every 1,000 pregnancies, at 10 weeks of gestation. Triploidy is important to identify early in pregnancy because it can lead to severe maternal complications. No other non-invasive test can detect triploidy – only Panorama.
  5. Sex chromosome aneuploidies , including XXY, XXX, XYY, and Monosomy X. Panorama is the only cfDNA-based test that reported fetal sex correctly in all validation studies (combined 1,002/1,002).

Why the Panorama test?

The Panorama™ test brings you:

  • A safe option for prenatal testing: unlike invasive procedures, Panorama is not associated with a risk of miscarriage
  • Information in the first trimester (gives information earlier than any other test): testing can be performed as early as 9 weeks gestation and then throughout the pregnancy
  • The most accurate results in the industry: our clinical data is unparalleled:
  • >99% accuracy for Down syndrome and for two not as common but important conditions, Patau and Edwards syndromes
  • >99% accuracy for triploidy, an important condition to identify for both the baby and the mother
  • >99% accuracy for identifying the sex of the baby
  • Has a decreased chance of false positives or false negatives with a low no call rate.
  • Results returned in 14 calendar days.
  • A comfortable option for prenatal testing:the screening test is taken from mother’s blood draw. The samples are delivered by a fast courier to Natera laboratory in California, USA.
  • Information about your baby’s sex.

What kind of information does the Panorama test give?


A high risk result means there is an increased and a very high that your baby has any of the chromosome conditions named. It is recommended to perform amniocentesis or chorionic villus sampling (CVS).


A low risk result means the chance that your baby has one of the chromosome conditions screened for is very low.

The test can give probabilistic information about named syndromes, but it does not answer the question whether the baby is going to be healthy when born.

Indications for considering the Panorama test:

  • Maternal age 35 years or older at delivery.
  • Fetal ultrasonographic findings indicating an increased risk of aneuploidy.
  • Positive test result for aneuploidy.
  • History of a prior pregnancy with a trisomy, including first trimester, sequential, or integrated screen, or a quadruple screen.
  • Parental balanced Robertsonian translocation with increased risk of fetal trisomy 13 or trisomy 21 (Down syndrome or Patau syndrome).

Panorama offers now screening for twin, egg donor, and surrogate pregnancies

Screening for twins:

Panorama is the only non-invasive prenatal blood test that can tell you whether your twins are identical or fraternal.

Panorama can distinguish between each twin’s DNA, which means you will get the information:

  • Whether your twins are identical (from the same egg) or fraternal or non-identical (from separate eggs)
  • The gender of each twin

Why it is important to know whether the twins are identical or not?

This information helps your healthcare provider to determine the appropriate amount of follow-up and what specialists may be necessary for your pregnancy. Identical twins may share a placenta. A shared placenta can increase the chance for unequal growth and a severe condition called twin-twin transfusion syndrome (TTTS). There is no risk of TTTS for fraternal twins.

Panorama can provide risk evaluation for more conditions than any other non-ivasive prenatal test for twins:

  • Down syndrome, Edwards syndrome, and Patau syndrome
  • Turner syndrome, a genetic disorder that occurs in girls that is associated with heart defects, learning difficulties, and infertility*
  • 22q11.2 deletion syndrome, a genetic disorder that occurs in boys and girls that is associated with learning differences, heart defects, and other birth defects*

*Risk evaluation available for pregnancies determined by Panorama to involve identical twins

For twin pregnancies, only Panorama can provide:

  • Zygosity information
  • Individual fetal fractions for dizygotic twins
  • Fetal sex for each twin
  • Monosomy X risk for monozygotic twins

Panorama helps clinicians identify higher risk for conditions that affect more than 1 in 45 twin pregnancies.

Screening for egg donor pregnancies

Conditions screened in  egg donor pregnancies:

    • Trisomy 21 (also known as Down syndrome)
    • Trisomy 18 (also known as Edwards syndrome)
    • Trisomy 13 (also known as Patau syndrome)


The cost of the Panorama prenatal test is 400 EUR.

The cost of the Panorama prenatal test + microdeletions test 550 EUR

More information:

Look also: Panorama Microdeletions Consent Form